Her long-term projects have been intensive interventions on the institutional structure of collective memory, education and politics.

Recognized as one of the 100 Leading Global Thinkers by Foreign Policy magazine, she is a 2015 Herb Alpert Award winner, a Hugo Boss Prize finalist, a Yale World Fellow and is the first artist-in-residence in the New York City Mayor's Office of Immigrant Affairs (MOIA). In 2013 she was part of the team creating the first document on artistic freedom and cultural rights with the United Nation's Human Rights Council. Her survey show, the inaugural Neuberger Prize, in 2010 was selected best show at a University Gallery by the International Association of Art Critics (AICA). Her work was exhibited at Documenta 11 (Kassel), Venice Biennale, Tate Modern, Guggenheim and Van Abbemuseum among others. Bruguera recently mounted a solo show at the Museum of Modern Art and will have an upcoming solo show at the Tate Modern.

Bruguera continues working on the political rights of migrants through her long-term project Immigrant Movement International and in May 2015 opened the Hannah Arendt International Institute for Artivism, in Havana.