Perry has exhibited in group shows at the Seattle Art Museum, Seattle, Washington, MoMA PS1, Queens, New York, and the Studio Museum in Harlem, Harlem, New York. The artist has participated in residencies at the Skowhegan School of Painting and Sculpture, Vermont Studio Center, Ox-Bow School of Art and Artists' Residency, the Experimental Television Center, and was recently an artist in residence at the prestigious CORE Residency Program at the Glassell School of Art at the Museum of Fine Arts, Houston.

Perry received a BFA from the New York State College of Ceramics at Alfred University in 2012 and a MFA from "an expensive New York art school causing gentrification in Harlem" in 2015. To describe her work, Sondra Perry manifests paraspaces, a term coined by science fiction author Samuel Delany, meaning a ‘space' existing parallel to the normal or ordinary, through performance and video. These paraspaces are phantom and twilight zones, her grandma's attic, and corners behind bookshelves where dead skin cells, lost candy corn, and little black girls find their autonomy. In these spaces, she and the viewer explore how imaging, visual languages, and digital literacy structure identity and representation in the virtual and physical realms.